Publications

Published work from Liu Lab and collaborators.

Research spanning molecular biosensors, optogenetics, advanced microscopy, computation and quantitative cell biology.

21 publications · 2010–2025

2025

21

Combined learning for augmented super-resolution imaging

Ren C, Pan T, Yang T, Yin N, Gu L, Liu B, Ji W

Optics & Laser Technology 192, 113943

10.1016/j.optlastec.2025.113943

2024

20

Live-cell biosensors based on the fluorescence lifetime of environment-sensing dyes

Mehl BP, Vairaprakash P, Li L, Hinde E, MacNevin CJ, Hsu CW, Gratton E, Liu B*, Hahn KM*

Cell Reports Methods 4, 100734

10.1016/j.crmeth.2024.100734

2023

19

Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C)

Bodrug T, Welsh KA, Bolhuis DL, et al.

Nature Structural & Molecular Biology 30, 1663-1674

10.1038/s41594-023-01105-5
18

Targeting small GTPases: emerging grasps on previously untamable targets, pioneered by KRAS

Yin G, Huang J, Petela J, et al.

Signal Transduction and Targeted Therapy 8, 212

10.1038/s41392-023-01441-4

2022

17

Spatial models of pattern formation during phagocytosis

Herron JC, Hu S, Liu B, et al.

PLoS Computational Biology 18(10), e1010092

10.1371/journal.pcbi.1010092
16

Actin nano-architecture of phagocytic podosomes

Herron JC, Hu S, Watanabe T, Nogueira AT, Liu B, Kern ME, et al.

Nature Communications 13, 4363

10.1038/s41467-022-32038-0

2021

15

Biosensors based on peptide exposure show single molecule conformations in live cells

Liu B*, Stone O*, Pablo M*, et al.

Cell 184(22), 5670-5685.e23

10.1016/j.cell.2021.09.026

2020

14

Deep learning enables structured illumination microscopy with low light levels and enhanced speed

Jin L*, Liu B*#, Zhao F, et al.

Nature Communications 11, 1934 (co-first, co-corresponding)

10.1038/s41467-020-15784-x
13

Engineering Optogenetic Protein Analogs

Liu B, Marston DJ, Hahn KM

Methods in Molecular Biology 2173, 113-126

10.1007/978-1-0716-0755-8_7

2019

12

Optogenetic control of cofilin and αTAT in living cells using Z-lock

Stone O*, Kaul N*, Liu B*, et al.

Nature Chemical Biology 15, 1183-1190 (co-first)

10.1038/s41589-019-0405-4
11

VIEW-MOD: a versatile illumination engine with a modular optical design for fluorescence microscopy

Liu B*, Hobson C*, et al.

Optics Express 27, 19950-19972

10.1364/oe.27.019950

2016

10

Ratiometric Imaging Using a Single Dye Enables Simultaneous Visualization of Rac1 and Cdc42 Activation

MacNevin CJ*, Toutchkine A, Marston DJ, Hsu CW, Tsygankov D, Li L, Liu B, Qi T, Nguyen DV, Hahn KM

Journal of the American Chemical Society 138, 2571-2575

10.1021/jacs.5b09764.s001

2015

9

Three-dimensional super-resolution protein localization correlated with vitrified cellular context

Liu B*, Xue Y*, Zhao W*, et al.

Scientific Reports 5

10.1016/j.bpj.2014.11.2595
8

The effect of the size of fluorescent dextran on its endocytic pathway

Li L, Wan T, Wan M, Liu B, Cheng R, Zhang R

Cell Biology International 39(5), 531-539

10.1002/cbin.10424

2014

7

SEC-10 and RAB-10 coordinate basolateral recycling of clathrin-independent cargo through endosomal tubules in Caenorhabditis elegans

Chen S*, Li L*, Li J*, Liu B, et al.

PNAS 111(43), 15432-15437

10.1073/pnas.1408327111
6

Potential phosphorylation site modulates the dimerization and activity of KIF1A

Liu B, Yue Y, Yu Y, Ren JQ, Feng W, Huo L, Xu T

Progress in Biochemistry and Biophysics 41(9), 870-876

5

A machine learning-based method to detect fluorescent spots and an accelerated, parallel implementation of this method

Liu B, Feng W, Xu T, Ji W

Science Bulletin 59, 3573-3578

10.1007/s11434-014-0385-4

2013

4

Ultrafast, accurate, and robust localization of anisotropic dipoles

Zhang Y, Gu L, Chang H, Ji W, Chen Y, Zhang M, Yang L, Liu B, Chen L, Xu T

Protein & Cell 4(8), 598-606

10.1007/s13238-013-3904-1

2012

3

A unique series of reversibly switchable fluorescent proteins with beneficial properties for various applications

Chang H*, Zhang M*, Ji W*, Chen J, Zhang Y, Liu B, Lu J, Zhang J, Xu P, Xu T

PNAS

10.1073/pnas.1113770109
2

Rational design of true monomeric and bright photoactivatable fluorescent proteins

Zhang M*, Chang H*, Zhang Y*, Yu J, Wu L, Ji W, Chen J, Liu B, Lu J, Liu Y, Zhang J, Xu P, Xu T

Nature Methods

10.1038/nmeth.2021

2010

1

UNC-31/CAPS docks and primes dense core vesicles in C. elegans neurons

Lin XG, Ming M, Chen MR, Niu WP, Zhang YD, Liu B, Jiu YM, Yu JW, Xu T, Wu ZX

Biochemical and Biophysical Research Communications 397(3), 526-531

10.1016/j.bbrc.2010.05.148